Acute Organophosphate poisoning This is the syndrome recognised by doctors and Poisons Units. Signs and symptoms are not listed in order of presentation or specificity. Presentation is highly variable due to differences in dose, agent toxicity, and type of exposure. Exposure by inhalation results in the fastest appearance of toxic symptoms, followed by the oral route and finally the dermal route. Sick dogs have a depressed immunity system and exposure to any insecticide can affect them greatly. The organophosphates (OPs) are derivatives of phosphoric or phosphonic acid. Organophosphate poisoning is a neurological syndrome caused by exposure to organophosphate chemicals like those found in insecticides, herbicides, and some nerve agents. 2-PAM (1 to 2 g in adults; 20 to 40 mg/kg in children) is given over 15 to 30 minutes IV after exposure to an organophosphate or carbamate because, frequently, whether the poison is an organophosphate or carbamate is unknown at the time of treatment. Poisoning can occur due to occupational or accidental exposure, deliberate ingestion, or chemical warfare with nerve gases. OPs have replaced the banned organochlorine compounds and are a major cause of animal poisoning. It is common in developing countries. They vary greatly in toxicity, residue levels, and excretion. All signs and symptoms are cholinergic in nature and affect Frozen stomach and rumen contents should be analyzed for the pesticide. Organophosphate Poisoning. Pralidoxime (2-PAM) is given after atropine to relieve neuromuscular symptoms. Signs and symptoms of organophosphate poisoning can be divided into three broad categories: (1) muscarinic effects, (2) nicotinic effects, and (3) central nervous system (CNS) effects. The cholinergic syndrome is caused by … Patients exposed to high quantities of these chemicals can develop a variety of symptoms and … Blood/serum, liver, and urine can … OP poisoning can occur in a variety of situations and can be accidental or suicidal. The following is a list of possible symptoms of organophosphate poisoning. Symptoms of Organophosphate Poisoning. The following is a more comprehensive list of signs and symptoms that may be encountered in a person exposed to a nerve agent or OP pesticide. Nerve Agent and Organophosphate Pesticide Poisoning. Before using any product containing organophosphate on any sick dog, consult a veterinarian. Organophosphate intoxication causes cholinergic symptoms early and subsequently a neuropathy with axonal degeneration producing muscle cramping and calf pain along with tingling and burning sensations in the feet. Diagnostic determination of organophosphate poisoning is often accomplished by confirming reduced acetylcholinesterase (AChE) activity in blood or brain. The present review discusses the structure of the anticholinesterase organophosphates (OPs), which are used predominantly as insecticides. Symptoms occur within 24 hours of exposure and include collapse, breathing problems, sweating, diarrhoea, vomiting, excessive salivation, heart dysrrhythmias, extreme anxiety … Symptoms of acute organophosphate poisoning develop during or after exposure, within minutes to hours, depending on method of exposure.
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