Under-the-tongue (sublingual) nitro- glycerin tablets are perhaps the best-known version of this common medication. Nitroglycerin can be toxic to children and pets. Other brands: Nitrostat, Nitro-Dur, NitroQuick, Nitro-Bid, ... +11 more, amlodipine, aspirin, metoprolol, lisinopril, losartan, furosemide, hydrochlorothiazide, carvedilol, atenolol, Lasix. Last updated on Mar 24, 2020. People can also use nitroglycerin to treat anal fissures. This promotes blood flow to the area and helps heal the fissure. You may get a headache when you use nitroglycerin. If this is too painful, the person may apply the ointment to the outside of the anus instead. 2 doctors agree. is ok to take long term? Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Nitroglycerin is used to treat or prevent attacks of chest pain (angina). Opening or widening blood vessels results in improved blood flow to … Nitroglycerin is usually taken at the first sign of chest pain. Discontinue if blurred vision develops. Most people place the patch on their chest. Nitroglycerin ER [Package Insert]. Always sit or stand up slowly when rising from a lying down or seated position as nitroglycerin may cause a drop in blood pressure. People can also treat anal fissures with nitroglycerin rectal ointment. There was a very high incidence of adverse reactions. Nitroglycerin helps widen the blood vessels so more blood gets to your heart muscle. Nitroglycerin is a type of nitrate. Contact your doctor immediately if you develop a slow heartbeat or new or worsening chest pain after using nitroglycerin. Dr. Saptarshi Bandyopadhyay answered. Spray the dose of Nitrolingual preferably onto or under the tongue; do not inhale. Nitroglycerin may also be used for purposes not listed in this medication guide. People can get anal fissures from passing hard stools. People often use the drug nitroglycerin to relieve chest pain that angina causes. You should refer to the prescribing information for nitroglycerin for a complete list of interactions. Talk to your doctor about taking nitroglycerin five to ten minutes before any activity that typically causes you chest pain. Keep well out of reach. This includes chest pain from a heart attack. Copyright 1996-2021 Drugs.com. The rectal ointment for anal fissures contains 0.4% nitroglycerin. Revised 12/2019. If someone has taken three doses of either fast-acting formulations and does not experience any pain relief, they should seek medical attention immediately. Nitroglycerin will start working within 1 to 3 minutes, but its maximal effect occurs after 5 minutes. Common side effects include headache and low blood pressure. Nitroglycerin is a medication that treats angina and chronic anal fissures. All rights reserved. Nitroglycerin may interact with certain other medications. This allows the arteries and veins to open up, allowing more blood to flow through. Nitroglycerin systemic 2.5 mg (ETHEX 004). Transdermal nitroglycerin, nitroglycerin ointment and capsules do not act rapidly enough to be used for acute anginal attacks. These headaches may gradually become less severe as you continue to use nitroglycerin. Nitroglycerin spray is used to treat episodes of angina (chest pain) in people who have coronary artery disease (narrowing of the blood vessels that supply blood to the heart). Use supportive treatment in overdose Doctors will not prescribe nitroglycerin to anyone with a history of severe anemia, heart attack occurring on the right side of the heart, or increased pressure in the brain. Tablets which have this taste when fresh but subsequently become tasteless may … People also use nitroglycerin to treat chronic anal fissures. they are only things that help. Nitroglycerin allows the blood vessels to open up, which lets oxygen and nutrient-rich blood feed the heart muscle. Nitroglycerin and related drugs, known as nitrates, widen the arteries that nourish the heart and reduce the heart's workload. A person places the patch on their skin anywhere except the areas below the knee and elbow. How does it work? However, if you are experiencing chest pain, which is unrelieved by one nitroglycerin dose, it is acceptable to have another dose and call for urgent medical help. When something restricts blood flow to the heart muscle, a person can experience intense chest pain that doctors call angina. MNT is the registered trade mark of Healthline Media. Chemically, the substance is an organic nitrate compound rather than a nitro compound, yet the traditional name is often retained. A sublingual packet of nitroglycerin contains 400 micrograms (mcg) of nitroglycerin powder. Nitroglycerin is in a class of medications called vasodilators. An overdose of nitroglycerin may occur when people use PDE-5 inhibitors with nitroglycerin or if they use too much nitroglycerin during an attack. Nitroglycerin patches come in doses ranging from 0.1 milligrams per hour (mg/hr) to 0.8 mg/hr. Even when effective, 75% of patients reported an adverse reaction. Doctors usually use nitroglycerin to treat the pain that angina causes. Nitroglycerin is used to treat or prevent attacks of chest pain (angina). Sometimes nitroglycerin will cause burning or stinging in your mouth, and sometimes it won't. Viagra, Cialis, and Levitra are PDE-5 inhibitors. Everything you need to know about heart disease, What to know about coronary heart disease, Debra Sullivan, Ph.D., MSN, R.N., CNE, COI, increased blood flow and pressure in the brain. Tell other health professionals (such as your dentist) that you take nitroglycerin. Narrowing of the arteries that supply the heart with blood is what causes unstable angina. antidepressants, such as amitriptyline, amoxapine, clomipramine, antipsychotics, such as aripiprazole, clozapine, haloperidol, nefazodone, or olanzapine, benzodiazepines, such as alprazolam, clobazam, clonazepam, lorazepam, or oxazepam, erectile dysfunction medications such as avanafil, sildenafil, tadalafil, or vardenafil, heart medications, such as benazepril, captopril, diltiazem, felodipine, or verapamil, migraine medications, such as ergotamine or dihydroergotamine, opioids, such as alfentanil, codeine, fentanyl, hydrocodone, or morphine, Parkinson's disease medications, such as cabergoline, rasagiline, or selegiline. As with nitroglycerin, these drugs also cause increased blood flow and can lower blood pressure. Learn more here. Select one or more newsletters to continue. When someone is having intense chest pain, it is vitalto resolve this symptom as quickly as possible. AvKARE, Inc. We comply with the HONcode standard for trustworthy health information -, https://www.drugs.com/pro/nitroglycerin-er.html. Alcohol, hot weather, and exercise may worsen these effects and result in fainting. People can also take fast-acting nitroglycerin formulations 5 to 10 minutes before doing an activity that may cause an angina attack. Invented in 1847, nitroglycerin has been used ever since as an active ingredient i… If they stand up too quickly after administering the dose, their blood pressure may drop even lower and put them at risk of fainting. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. It has a very short duration of action and may not be suitable for some people. Alcohol toxicity has been reported when high-dose nitroglycerin injection has been given in conjunction with alcohol, or when certain medications (such as disulfiram, cephalosporin antibiotics) are taken at the same time as nitroglycerin and alcohol. When Should You Take Nitroglycerin? The low blood pressure can be severe. Anal fissures are tears in the skin of the anus. What needs to be monitored when taking Nitroglycerin. Rarely, allergic reactions, flushing, severe dizziness, a headache, or persistent nausea or vomiting may occur. Decreased myocardial O2 contraction Decrease blood pressure Helps with chest pain Produces vasodilation Increases coronary blood flow Increases cardiac output. The body breaks nitroglycerin down into nitric oxide. More than 370,000 people in the United States die every year because of CAD. Some people may be allergic to nitroglycerin, and doctors do not recommend that people use it if they have a history of allergic reactions to nitroglycerin. May not be suitable for some people including seniors; those with a history of stroke or bleeding in the brain; with anemia, glaucoma, migraines, or swelling of the heart sac; taking medications for erectile dysfunction; or in people whose blood flow back to the heart is already restricted. Take exactly as directed by your doctor. Nitroglycerin will absorb through the mouth tissues. Nitroglycerin extended-release capsules are used to prevent chest pain (angina) in people with a certain heart condition (coronary artery disease). The coronary arteries supply oxygen and blood to the heart. The body breaks nitroglycerin down … People can apply nitroglycerin ointment to their skin using a dose-measuring applicator that comes with the tube. It is also used just before activities that may cause episodes of angina in order to prevent the angina from occurring. Do not take medicines for erectile dysfunction (ED), such as Viagra, Cialis or Levitra, while you are taking nitroglycerin as the combination may dangerously drop your blood pressure. It has a … Ask your doctor before using any headache pain medication. Do not change brands unintentionally as not all are bioequivalent. Nitroglycerin may also be used for purposes not listed in this medication guide. Do not rely on this as an indication that the medicine is or isn't working, because it is an unreliable indication. Do not rinse or spit nitroglycerin powder for 5 minutes after using the medicine. Nitroglycerin belongs to the group of medicines called nitrates. Although the rectal ointment is only put in the anus, a person may still experience headache and dizziness. Nitroglycerin (NTG) tablets placed under the tongue, is a very effective means of treating angina. Speak to your doctor about how drug interactions should be managed. Alcohol may increase the side effects of nitroglycerin. This results in…, Doctors mainly prescribe amlodipine (Norvasc) to treat people with high blood pressure, coronary artery disease, and angina. What is nitroglycerin, and how does it work? Heart disease is a major cause of death. At the first signs of angina pains, a person should place the tablet under their tongue or between the gums and the cheek. Nitroglycerin helps to open up the blood vessels and allow blood to flow. 38 years experience Cardiology. Nitroglycerin is a medication that treats angina and chronic anal fissures. Nitroglycerin can alleviate chest pain by relaxing the muscles in the walls of the blood vessels, causing them to dilate. Nitroglycerin sublingual tablets are used to treat episodes of angina (chest pain) in people who have coronary artery disease (narrowing of the blood vessels that supply blood to the heart). People can use these devices by giving one or two sprays on or under the tongue once a person feels angina pains. 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