0000011064 00000 n Appendix K. Review of ECOTOX database for dimethoate and omethoate Attachments Attachment 1: Status and Life History of California Red-legged Frog Attachment 2: Baseline Status and Cumulative Effects for the California Red-legged Frog List of Figures Figure 1. 0000028049 00000 n Dimethoate, omethoate and metabolites X, XVI and XVII exhibited low and very low persistence in soil which was confirmed in the confined rotational crops metabolism study conducted at the representative plant‐back intervals (PBIs) of 30 and 120 days in lettuces, turnips and wheat after a bare soil application of 0.56 kg a.s./ha (2.8 N rate). 0000031472 00000 n 0000032426 00000 n 0000009362 00000 n 0000020541 00000 n 0000022525 00000 n 0000020735 00000 n 0000019334 00000 n 0000033098 00000 n an anti-cholinesterase compound Registered For: Commercial use Domestic use. 0000032685 00000 n This work plan has been prepared to fulfill new legislative requirements intended to improve the transparency and predictability of chemical review decisions. 0000032066 00000 n 0000027844 00000 n The Meeting therefore recommended that residues of dimethoate and omethoate resulting from the use of dimethoate be expressed as dimethoate and be assessed in comparison with the ADI for dimethoate. Omethoate (O,O-dimethyl S-methylcarbamoylmethyl phosphorothioate) is a systemic organophosphorus insecticide and acaricide used to control insects and mites in horticulture and agriculture, as well as in the home garden. Omethoate (the oxygen analogue of dimethoate, which has been used as a pesticide in its own right) was evaluated for toxicological effects by the Joint Meeting in 1971, 1975, 1978, 1979, 1981, and 1985. 0000030687 00000 n Biochemical evidence that an S431F mutation in acetylcholinesterase-1 of Aphis gossypii mediates resistance to pirimicarb and omethoate (Pest Management Science, 2004); Sister-chromatid exchanges in human lymphocytes induced by dimethoate, omethoate, deltamethrin, benomyl and their mixture. 0000020033 00000 n 0000031384 00000 n The Meeting was informed that the primary manufacturer is no longer producing omethoate; however, since the use of dimethoate on agricultural crops can lead to residues of omethoate in treated produce, the toxicity of omethoate is important in the context of the potential use of dimethoate. Dimethoate Omethoate The present document was developed jointly between the U.S. EPA and Canada’s Pest Management Regulatory Agency (PMRA). Dimethoate. 0000027312 00000 n The compound was reviewed at the present Meeting within the CCPR periodic review programme. The NOAELs were thus generally based on reductions in acetylcholinesterase activity in the brain or erythrocytes. It acts both by contact and through ingestion. 0000010584 00000 n 0000033952 00000 n These data, together with all previously submitted registration data and relevant published data, have been assessed in detail. Use on alfalfa, wheat, cotton, and corn crops accounts for more than 60% of the total dimethoate use in the U.S. (U.S. EPA, 2006). 0000009080 00000 n 0000025389 00000 n Dimethoate Omethoate S O H H P N P N H3CO S CH3 H3CO S CH3 OCH3 OCH3 O O The present document was developed jointly between the U.S. EPA and Canada’s Pest Management Regulatory Agency (PMRA). Preparation of this review was aided by reference to the results of previous reviews conducted by the Pesticides Safety Directorate, United Kingdom. Surface-enhanced Raman spectra of dimethoate and omethoate. Add to Cart. 0000021972 00000 n 0000009832 00000 n 0000025716 00000 n 0000000016 00000 n 0000030075 00000 n In surface waters, dimethoate and O-desmethyl dimethoate are detected. Data and information have been submitted by the Dimethoate Task Force (BASF, Cheminova, and Isagro, via Scientific Consulting Co., Woellstein, Germany), Cheminova, and the governments of Australia, Germany, The Netherlands, Thailand, and the UK. dimethoate and omethoate residues at the time of consumption, the difference in toxicity was taken into account (1998 JMPR residue evaluations, p. 510) by multiplying the omethoate residues by a factor of 10 for calculation of the sum of the residues. As the use of dimethoate on crops can give rise to residues of omethoate, and omethoate has been used as a pesticide in its own right, previous Joint Meetings have allocated an ADI to omethoate; however, the primary manufacturer is no longer producing omethoate. 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